In this study, Pb(Ni1/3Nb2/3)O3-Pb(Zr,Ti)O3 ceramics substituted with Pb(Mg1/2W1/2)O3 were fabricated with the variation of CuO for application to ultrasonic cleaning of removable orthodontic appliances (ROA). And their piezoelectric and dielectric properties were investigated. At the 0.12 wt% CuO added ceramics sintered at 930℃, the excellent values of dielectric constant=2,519, density=7.82 g/㎤, kp=0.64, d33=536 pC/N, Qm=57 were obtained, respectively. These values were suitable for application to ultrasonic cleaning of ROA.