With polymer properties and ceramic volume fraction as design variables, the optimal structure of 1-3 piezocomposites has been determined to maximize the thickness mode electromechanical coupling factor. When the piezocomposite vibrates in a thickeness mode, inter-pillar resonant modes are likely to occur between lattice-structured piezoceramic pillars and polymer matrix, which significantly deteriorates the performance of the piezocomposite. In this work, work, a new method to design the structure of the 1-3 type piezocomposite is proposed to maximize the thickness mode electromechanical coupling factor while preventing the occurrence of the inter- pillar modes. Genetic algorithm was used for the optimal design, and the finite element analysis method was used for the analysis of the inter-pillar mode.